|Fortified Flax Hulls (with Broccoli Sprouts)|
|Flax Hulls - Metals Analysis|
|Effect of Lignans on Prostate Cancer|
|Lignans may Prevent Prostate Cancer|
|Breast Cancer - reports and trials|
|Testimonies from producer|
|New Therapies for Psoriasis|
|HRT - a significant breast cancer risk|
|Importance of fibre in diet|
|Antibiotics may increase chances of Breast Cancer|
|ASA may cut breast cancer risk: study|
|Milk may lower colon cancer risk|
|Study cast doubt on soy as menopause aid|
|Warning over HRT long-term use|
|Study shows Lignans help with hair loss|
|The First Steps to a Strong Immune System|
|Sulforaphane effective against H. Pylori|
|Sulforaphane - could fight Leukemia, cancers||
Lignans and Prostate Cancer Research
Effect of Lignans on prostate cancer
Lin X, Switzer BR, Denmark-Wahnefried W
Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USA.
ABSTRACT: Anticancer Res. 2001 Nov-Dec;21(6A):3995-9.
Mammalian lignans, enterolactone (EL) and enterodiol (ED), have been shown to inhibit breast and colon carcinoma.
To date, there have been no reports of the effect of lignans on prostatic carcinoma. We investigated the effects
of ED and EL on three human prostate cancer cell lines (PC-3, DU-145 and LNCaP).
MATERIALS AND METHODS:
Cells were treated with either 0.1% (v/v) DMSO (vehicle) or 10-100 microM of EL, ED or genistein (positive
control) for 72 hours. Cell viability was measured by the propidium iodide nuclei staining fluorometric assay with
each assay performed in triplicate.
At 10-100 microM, EL significantly inhibited the growth of all cell lines, whereas ED only inhibited PC-3 and LNCaP
cells. While EL was a more potent growth inhibitor than ED, both were less potent than genistein. The dose for 50%
growth inhibition of LNCaP cells (IC50) by EL was 57 microM, whereas IC50 was 100 microM for ED, (the observed IC50
for genistein was 25 microM)
ED and EL suppress the growth of prostate cancer cells, and may do so via hormonally-dependent and independent
Next Page - Flax's Ability to Prevent Prostate Cancer
See below for a sample of Fortified Flax Hulls (1st pic) and Flax Hulls (2nd pic)
Each jar contains 180gm of fortified flax hulls or 150gm of flax hulls
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