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 Prostate Cancer Info 
What is Prostate Cancer
Prostate Cancer Defined
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Effect of Lignans on Prostate Cancer
Lignans may Prevent Prostate Cancer

 

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Antibiotics may increase chances of Breast Cancer
ASA may cut breast cancer risk: study
Milk may lower colon cancer risk
Study cast doubt on soy as menopause aid
Warning over HRT long-term use
High Five for Fibre
Study shows Lignans help with hair loss
The First Steps to a Strong Immune System
Sulforaphane effective against H. Pylori
Sulforaphane - could fight Leukemia, cancers

Lignans and Prostate Cancer Research


Effect of Lignans on prostate cancer


Lin X, Switzer BR, Denmark-Wahnefried W
Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USA.


ABSTRACT: Anticancer Res. 2001 Nov-Dec;21(6A):3995-9.

BACKGROUND:
Mammalian lignans, enterolactone (EL) and enterodiol (ED), have been shown to inhibit breast and colon carcinoma. To date, there have been no reports of the effect of lignans on prostatic carcinoma. We investigated the effects of ED and EL on three human prostate cancer cell lines (PC-3, DU-145 and LNCaP).

MATERIALS AND METHODS:
Cells were treated with either 0.1% (v/v) DMSO (vehicle) or 10-100 microM of EL, ED or genistein (positive control) for 72 hours. Cell viability was measured by the propidium iodide nuclei staining fluorometric assay with each assay performed in triplicate.

RESULTS:
At 10-100 microM, EL significantly inhibited the growth of all cell lines, whereas ED only inhibited PC-3 and LNCaP cells. While EL was a more potent growth inhibitor than ED, both were less potent than genistein. The dose for 50% growth inhibition of LNCaP cells (IC50) by EL was 57 microM, whereas IC50 was 100 microM for ED, (the observed IC50 for genistein was 25 microM)

CONCLUSION:
ED and EL suppress the growth of prostate cancer cells, and may do so via hormonally-dependent and independent mechanisms.

Next Page - Flax's Ability to Prevent Prostate Cancer




See below for a sample of Fortified Flax Hulls (1st pic) and Flax Hulls (2nd pic)

    
Each jar contains 180gm of fortified flax hulls or 150gm of flax hulls




The above information is provided for general educational purposes only. It is not intended to replace competent health care advice received from a knowledgeable healthcare professional. You are urged to seek healthcare advice for the treatment of any illness or disease.
Health Canada and the FDA (USA) have not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.


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